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I would cut the ignition the second it loads up and starts to slow down. Come to a stop with the engine off, pull the plug, and read it. It may not be perfect, but it should give you a decent window into what is going on with the fueling (if it is the fueling) during wide open throttle.
Also, the mixture screw is for the idle mixture. Adjusting that isn't going to do much of anything to help wide open throttle.
Did the bike sit with any fuel in the carb, or with the petcock open, during the last 6 months? Did you run at those rpms and speeds previously? It may just be some junk blocking the main jet or the needle seat emulsion tube. Nothing a good cleaning couldn't fix.
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